Control of acidosis during exchange transfusion with citrated blood.

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Control of acidosis during exchange transfusion with citrated blood.

In a previous paper (Calladine et al., 1965) it was shown that during exchange transfusion with citrated blood an acidosis often developed in babies transfused on the first day of life, but not in those transfused on the third day or later. The acidosis in the babies concerned was sometimes severe, and was occasionally associated with clinical symptoms. It was concluded that in performing excha...

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Acid-base changes following exchange transfusion with citrated blood.

The acid-citrate-dextrose (ACD) solution used to preserve blood consists in effect of 2 parts trisodium citrate to 1 part citric acid. It forms a buffer solution such that the pH of bank blood less than 5 days old is, in our experience, 6 6 ± 0 * 2. It can be predicted, therefore, that infusion of ACD blood must lead to an initial acidosis, and that this will in due course be replaced by a meta...

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Acid-base Changes following Exchange Transfusion with Citrated Blood

The acid-citrate-dextrose (ACD) solution used to preserve blood consists in effect of 2 parts trisodium citrate to 1 part citric acid. It forms a buffer solution such that the pH of bank blood less than 5 days old is, in our experience, 6 6 ± 0 * 2. It can be predicted, therefore, that infusion of ACD blood must lead to an initial acidosis, and that this will in due course be replaced by a meta...

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Alterations in blood pressure during exchange transfusion.

Blood pressure changes as a function of the rates of blood withdrawal and infusion were determined during exchange blood transfusion in 2 preterm newborn infants. 10 ml blood withdrawal and infusion completed within 3 minutes resulted in reversible changes in aortic pressure, whereas the same procedure completed within 45 to 60 seconds resulted in a progressive fall in the systolic pressure and...

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The Electrocardiogram during Exchange Transfusion.

Exchange transfusion is a hazardous procedure with a mortality of 4-7 5%. (van Praagh, 1961; Boggs and Westphal, 1960). Various complications may lead to sudden death in which hyperkalaemia, hypocalcaemia, acidosis, citrate toxicity, circulatory overloading, hypothermia and embolism have been incriminated (Farquhar and Smith, 1958). The mode of death in these cases, whatever the aetiology, is u...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1968

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.43.228.147